Search on: MUSTARD COMPOUNDS 
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Descriptor English:   Mustard Compounds 
Descriptor Spanish:   Compuestos de Mostaza 
Descriptor Portuguese:   Compostos de Mostarda 
Synonyms English:   Compounds, Mustard  
Tree Number:   D02.455.526.728
Definition English:   Strong alkylating and immunosuppressive agents whose biological activity is based on the presence of bis(2-chloroethyl)- groups. Although otherwise structurally diverse, the compounds have in common the capacity to contribute alkyl groups to DNA. They are generally highly toxic but include among their number many widely used and effective antineoplastic agents. 
Indexing Annotation English:   DF: MUSTARD CPDS
History Note English:   68 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   21038 
Unique Identifier:   D009150 

Occurrence in VHL:
 

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